{"id":5678,"date":"2025-02-21T17:22:36","date_gmt":"2025-02-21T09:22:36","guid":{"rendered":"https:\/\/nullthought.net\/?p=5678"},"modified":"2025-02-23T11:08:04","modified_gmt":"2025-02-23T03:08:04","slug":"evo-2%ef%bc%9a%e6%b6%b5%e7%9b%96%e6%89%80%e6%9c%89%e7%94%9f%e5%91%bd%e9%a2%86%e5%9f%9f%e5%9f%ba%e5%9b%a0%e7%bb%84%e6%95%b0%e6%8d%ae%e9%9b%86%e7%9a%84%e7%94%9f%e7%89%a9%e5%ad%a6%e5%9f%ba%e7%a1%80","status":"publish","type":"post","link":"https:\/\/nullthought.net\/?p=5678","title":{"rendered":"Evo 2\uff1a\u6db5\u76d6\u6240\u6709\u751f\u547d\u9886\u57df\u57fa\u56e0\u7ec4\u6570\u636e\u96c6\u7684\u751f\u7269\u5b66\u57fa\u7840\u6a21\u578b"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">\u8bba\u6587<strong><a href=\"https:\/\/arcinstitute.org\/manuscripts\/Evo2\" target=\"_blank\" rel=\"noreferrer noopener\">Genome modeling and design across all domains of life with Evo 2<\/a><\/strong>\u4ecb\u7ecd\u4e86Evo 2\uff0c\u4e00\u4e2a\u8bad\u7ec3\u4e8e\u6db5\u76d6\u6240\u6709\u751f\u547d\u9886\u57df\u7684\u57fa\u56e0\u7ec4\u6570\u636e\u96c6\u7684\u751f\u7269\u5b66\u57fa\u7840\u6a21\u578b\uff0c\u8be5\u6a21\u578b\u53ef\u7528\u4e8e\u6df1\u5165\u7406\u89e3\u548c\u8bbe\u8ba1\u751f\u547d\u4e2d\u7684\u57fa\u56e0\u7ec4\u529f\u80fd\u3002Evo 2\u57289.3\u4e07\u4ebf\u4e2aDNA\u78b1\u57fa\u5bf9\u6570\u636e\u4e0a\u8bad\u7ec3\uff0c\u5e76\u80fd\u591f\u4ee5\u5355\u78b1\u57fa\u5206\u8fa8\u7387\u9884\u6d4b\u9057\u4f20\u53d8\u5f02\u7684\u529f\u80fd\u5f71\u54cd\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"790\" height=\"867\" src=\"https:\/\/nullthought.net\/wp-content\/uploads\/2025\/02\/image-14.png\" alt=\"\" class=\"wp-image-5681\" srcset=\"https:\/\/nullthought.net\/wp-content\/uploads\/2025\/02\/image-14.png 790w, https:\/\/nullthought.net\/wp-content\/uploads\/2025\/02\/image-14-273x300.png 273w, https:\/\/nullthought.net\/wp-content\/uploads\/2025\/02\/image-14-768x843.png 768w\" sizes=\"auto, (max-width: 790px) 100vw, 790px\" \/><figcaption class=\"wp-element-caption\"><strong><a href=\"https:\/\/arcinstitute.org\/manuscripts\/Evo2\" target=\"_blank\" rel=\"noreferrer noopener\">Genome modeling and design across all domains of life with Evo 2<\/a><\/strong><\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">\u8bba\u6587\u4f5c\u8005\u548c\u6240\u5c5e\u673a\u6784\u5982\u4e0b\uff1a<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"944\" height=\"489\" src=\"https:\/\/nullthought.net\/wp-content\/uploads\/2025\/02\/image-15.png\" alt=\"\" class=\"wp-image-5682\" srcset=\"https:\/\/nullthought.net\/wp-content\/uploads\/2025\/02\/image-15.png 944w, https:\/\/nullthought.net\/wp-content\/uploads\/2025\/02\/image-15-300x155.png 300w, https:\/\/nullthought.net\/wp-content\/uploads\/2025\/02\/image-15-768x398.png 768w\" sizes=\"auto, (max-width: 944px) 100vw, 944px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4e00\u3001\u5f15\u8a00<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u751f\u7269\u5b66\u7814\u7a76\u7684\u6838\u5fc3\u4e4b\u4e00\u662f\u63ed\u793aDNA\u4e2d\u4fe1\u606f\u7684\u7f16\u7801\u65b9\u5f0f\uff0cDNA\u5728\u6240\u6709\u751f\u547d\u5f62\u5f0f\u4e2d\u626e\u6f14\u7740\u81f3\u5173\u91cd\u8981\u7684\u89d2\u8272\u3002\u968f\u7740\u57fa\u56e0\u7ec4\u5b66\u5de5\u5177\u7684\u53d1\u5c55\uff0c\u57fa\u56e0\u6d4b\u5e8f\u3001\u57fa\u56e0\u5408\u6210\u4ee5\u53ca\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u4e3a\u751f\u7269\u5b66\u7814\u7a76\u5e26\u6765\u4e86\u5de8\u5927\u7a81\u7834\u3002\u7136\u800c\uff0c\u5c3d\u7ba1\u8fd9\u4e9b\u6280\u672f\u80fd\u591f\u5e2e\u52a9\u6211\u4eec\u7406\u89e3DNA\u5e8f\u5217\u548c\u751f\u7269\u5b66\u529f\u80fd\u4e4b\u95f4\u7684\u5173\u7cfb\uff0c\u8981\u8bbe\u8ba1\u65b0\u7684\u751f\u7269\u7cfb\u7edf\uff0c\u4ecd\u7136\u9700\u8981\u66f4\u6df1\u5165\u7684\u7406\u89e3\u57fa\u56e0\u7ec4\u7684\u590d\u6742\u6027\u3002\u4e3a\u6b64\uff0c\u7814\u7a76\u4eba\u5458\u63d0\u51fa\u4e86Evo 2\u6a21\u578b\uff0c\u5b83\u662f\u4e00\u4e2a\u751f\u7269\u5b66\u57fa\u7840\u6a21\u578b\uff0c\u901a\u8fc7\u5728\u5305\u542b9.3\u4e07\u4ebfDNA\u78b1\u57fa\u5bf9\u7684\u8bad\u7ec3\u96c6\u4e0a\u8fdb\u884c\u5b66\u4e60\uff0c\u80fd\u591f\u51c6\u786e\u5730\u9884\u6d4b\u9057\u4f20\u53d8\u5f02\u5bf9\u57fa\u56e0\u7ec4\u529f\u80fd\u7684\u5f71\u54cd\u3002Evo 2\u5728\u4e0d\u8fdb\u884c\u7279\u5b9a\u4efb\u52a1\u5fae\u8c03\u7684\u60c5\u51b5\u4e0b\uff0c\u53ef\u4ee5\u901a\u8fc7\u5355\u7eaf\u5206\u6790DNA\u5e8f\u5217\uff0c\u9884\u6d4b\u53d8\u5f02\u7684\u529f\u80fd\u6548\u5e94\uff0c\u5305\u62ec\u975e\u7f16\u7801\u7a81\u53d8\u548c\u4e34\u5e8a\u4e0a\u6709\u91cd\u8981\u610f\u4e49\u7684BRCA1\u7a81\u53d8\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4e8c\u3001Evo 2\u6a21\u578b\u67b6\u6784\u4e0e\u8bad\u7ec3\u8fc7\u7a0b<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Evo 2\u91c7\u7528\u4e86\u4e00\u79cd\u591a\u6df7\u5408\u5377\u79ef\u67b6\u6784\uff08StripedHyena 2\uff09\uff0c\u8fd9\u662f\u7b2c\u4e00\u4e2a\u57fa\u4e8e\u8f93\u5165\u4f9d\u8d56\u5377\u79ef\u64cd\u4f5c\u7b26\u7684\u591a\u6df7\u5408\u67b6\u6784\u3002\u8be5\u67b6\u6784\u901a\u8fc7\u7ed3\u5408\u4e09\u79cd\u4e0d\u540c\u7c7b\u578b\u7684\u5377\u79ef\u8fd0\u7b97\u7b26\uff08\u77ed\u3001\u957f\u548c\u4e2d\u7b49\u957f\u5ea6\u7684\u5377\u79ef\uff09\uff0c\u663e\u8457\u63d0\u9ad8\u4e86\u5927\u89c4\u6a21\u8bad\u7ec3\u7684\u6548\u7387\uff0c\u4f7f\u5f97Evo 2\u80fd\u591f\u5904\u7406\u957f\u8fbe100\u4e07\u78b1\u57fa\u5bf9\u7684DNA\u5e8f\u5217\u3002\u76f8\u6bd4\u4f20\u7edf\u7684Transformer\u67b6\u6784\uff0cEvo 2\u5728\u5927\u89c4\u6a21\u8bad\u7ec3\u4e2d\u7684\u901f\u5ea6\u66f4\u5feb\uff0c\u5904\u7406\u66f4\u957f\u5e8f\u5217\u65f6\u8868\u73b0\u66f4\u52a0\u9ad8\u6548\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Evo 2\u5728OpenGenome2\u6570\u636e\u96c6\u4e0a\u8fdb\u884c\u8bad\u7ec3\uff0c\u8be5\u6570\u636e\u96c6\u5305\u542b\u6765\u81ea\u7ec6\u83cc\u3001\u53e4\u83cc\u3001\u771f\u6838\u751f\u7269\u548c\u75c5\u6bd2\u7684\u57fa\u56e0\u7ec4\u5e8f\u5217\uff0c\u6570\u636e\u7684\u603b\u91cf\u8fbe\u5230\u4e869.3\u4e07\u4ebf\u4e2atoken\u3002\u8bad\u7ec3\u8fc7\u7a0b\u5206\u4e3a\u4e24\u4e2a\u9636\u6bb5\uff1a\u7b2c\u4e00\u9636\u6bb5\u662f\u9884\u8bad\u7ec3\uff0c\u4f7f\u7528\u8f83\u77ed\u7684\u4e0a\u4e0b\u6587\u7a97\u53e3\uff088,192\u4e2atoken\uff09\uff0c\u91cd\u70b9\u5b66\u4e60\u529f\u80fd\u6027\u57fa\u56e0\u5143\u7d20\uff1b\u7b2c\u4e8c\u9636\u6bb5\u662f\u4e2d\u671f\u8bad\u7ec3\uff0c\u5c06\u4e0a\u4e0b\u6587\u7a97\u53e3\u6269\u5c55\u52301\u767e\u4e07\u4e2atoken\uff0c\u4ee5\u5b66\u4e60\u57fa\u56e0\u7ec4\u5e8f\u5217\u4e2d\u5404\u4e2a\u5143\u7d20\u4e4b\u95f4\u7684\u957f\u8ddd\u79bb\u5173\u7cfb\u3002Evo 2\u7684\u8bad\u7ec3\u6570\u636e\u6ca1\u6709\u5305\u542b\u611f\u67d3\u771f\u6838\u751f\u7269\u7684\u75c5\u6bd2\u57fa\u56e0\u7ec4\uff0c\u8fd9\u4e00\u6570\u636e\u9009\u62e9\u6709\u52a9\u4e8e\u907f\u514d\u6a21\u578b\u5728\u8be5\u9886\u57df\u7684\u8bed\u8a00\u5efa\u6a21\u80fd\u529b\u504f\u5f31\uff0c\u786e\u4fdd\u5176\u5728\u5176\u4ed6\u9886\u57df\u7684\u6709\u6548\u6027\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4e09\u3001Evo 2\u7684\u9884\u6d4b\u4e0e\u751f\u6210\u80fd\u529b<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Evo 2\u7684\u80fd\u529b\u4e0d\u4ec5\u4ec5\u5c40\u9650\u4e8e\u57fa\u56e0\u7a81\u53d8\u7684\u9884\u6d4b\uff0c\u5b83\u8fd8\u80fd\u591f\u751f\u6210\u65b0\u7684\u57fa\u56e0\u7ec4\u5e8f\u5217\uff0c\u5e76\u5728\u591a\u4e2a\u751f\u7269\u5b66\u4efb\u52a1\u4e2d\u8868\u73b0\u51fa\u8272\u3002Evo 2\u901a\u8fc7\u201c\u96f6\u6837\u672c\uff08zeor-shot\uff09\u201d\u5b66\u4e60\uff0c\u65e0\u9700\u8fdb\u884c\u7279\u5b9a\u4efb\u52a1\u7684\u5fae\u8c03\uff0c\u5373\u53ef\u5bf9DNA\u3001RNA\u548c\u86cb\u767d\u8d28\u7a81\u53d8\u7684\u5f71\u54cd\u8fdb\u884c\u9884\u6d4b\u3002\u5728\u201c\u96f6\u6837\u672c\uff08zeor-shot\uff09\u201d\u4efb\u52a1\u4e2d\uff0cEvo 2\u8868\u73b0\u51fa\u8272\uff0c\u80fd\u591f\u9884\u6d4b\u7a81\u53d8\u5bf9\u5206\u5b50\u529f\u80fd\u548c\u6709\u673a\u4f53\u9002\u5e94\u6027\u7684\u5f71\u54cd\uff0c\u5c24\u5176\u5728\u975e\u7f16\u7801\u533a\u57df\u548c\u526a\u63a5\u53d8\u5f02\u7684\u9884\u6d4b\u4e0a\u8868\u73b0\u7a81\u51fa\u3002\u7814\u7a76\u4eba\u5458\u8fd8\u53d1\u73b0\uff0cEvo 2\u80fd\u591f\u9884\u6d4b\u5404\u79cd\u7a81\u53d8\u7c7b\u578b\uff0c\u5305\u62ec\u975e\u540c\u4e49\u7a81\u53d8\u3001\u9519\u4e49\u7a81\u53d8\u3001\u63d2\u5165\u6216\u7f3a\u5931\uff08indels\uff09\u7b49\uff0c\u5bf9\u5176\u6f5c\u5728\u81f4\u75c5\u6027\u3001\u526a\u63a5\u6548\u5e94\u53ca\u751f\u7269\u5b66\u529f\u80fd\u8fdb\u884c\u7cbe\u51c6\u8bc4\u5206\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Evo 2\u5728\u57fa\u56e0\u7ec4\u5e8f\u5217\u751f\u6210\u65b9\u9762\u4e5f\u8868\u73b0\u51fa\u8272\u3002\u8be5\u6a21\u578b\u53ef\u4ee5\u751f\u6210\u5b8c\u6574\u7684\u57fa\u56e0\u7ec4\u5e8f\u5217\uff0c\u5305\u62ec\u7ebf\u7c92\u4f53\u57fa\u56e0\u7ec4\u3001\u6700\u5c0f\u7ec6\u83cc\u57fa\u56e0\u7ec4\u548c\u9175\u6bcd\u67d3\u8272\u4f53\u7b49\uff0c\u751f\u6210\u7684\u5e8f\u5217\u5177\u6709\u6bd4\u4ee5\u524d\u6a21\u578b\u66f4\u9ad8\u7684\u81ea\u7136\u6027\u548c\u8fde\u8d2f\u6027\u3002\u8fd9\u610f\u5473\u7740Evo 2\u4e0d\u4ec5\u80fd\u591f\u751f\u6210\u7b26\u5408\u751f\u7269\u5b66\u7279\u6027\u7684\u57fa\u56e0\u5e8f\u5217\uff0c\u8fd8\u80fd\u591f\u751f\u6210\u5177\u6709\u751f\u7269\u5b66\u529f\u80fd\u7684\u5e8f\u5217\u3002\u8fd9\u4e00\u80fd\u529b\u4e3a\u5408\u6210\u751f\u7269\u5b66\u63d0\u4f9b\u4e86\u91cd\u8981\u5de5\u5177\uff0c\u80fd\u591f\u7528\u4e8e\u521b\u5efa\u65b0\u7684\u751f\u7269\u4f53\u6216\u8c03\u8282\u73b0\u6709\u751f\u7269\u4f53\u7684\u57fa\u56e0\u7ec4\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56db\u3001\u673a\u5236\u53ef\u89e3\u91ca\u6027\u4e0e\u7279\u5f81\u5206\u6790<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Evo 2\u901a\u8fc7\u5148\u8fdb\u7684\u673a\u5236\u53ef\u89e3\u91ca\u6027\u65b9\u6cd5\uff0c\u63ed\u793a\u4e86\u5176\u5185\u90e8\u8868\u793a\u7684\u751f\u7269\u5b66\u7279\u5f81\u3002\u7814\u7a76\u56e2\u961f\u5229\u7528\u7a00\u758f\u81ea\u7f16\u7801\u5668\uff08SAEs\uff09\u5bf9Evo 2\u7684\u795e\u7ecf\u5143\u6fc0\u6d3b\u6a21\u5f0f\u8fdb\u884c\u89e3\u7801\uff0c\u4ece\u800c\u53d1\u73b0\u4e86\u4e00\u4e9b\u91cd\u8981\u7684\u751f\u7269\u5b66\u7279\u5f81\u3002\u901a\u8fc7\u8fd9\u4e9b\u7279\u5f81\u5206\u6790\uff0c\u7814\u7a76\u4eba\u5458\u8bc6\u522b\u51fa\u4e86\u4e0e\u5916\u663e\u5b50-\u5185\u542b\u5b50\u8fb9\u754c\u3001\u8f6c\u5f55\u56e0\u5b50\u7ed3\u5408\u4f4d\u70b9\u3001\u86cb\u767d\u8d28\u7ed3\u6784\u5143\u7d20\u3001\u566c\u83cc\u4f53\u57fa\u56e0\u7ec4\u533a\u57df\u7b49\u5bc6\u5207\u76f8\u5173\u7684\u7279\u5f81\u3002\u8fd9\u4e9b\u7279\u5f81\u4e0d\u4ec5\u5e2e\u52a9\u6211\u4eec\u7406\u89e3Evo 2\u662f\u5982\u4f55\u5b66\u4e60\u5e76\u5904\u7406\u57fa\u56e0\u7ec4\u6570\u636e\u7684\uff0c\u8fd8\u53ef\u4ee5\u5e94\u7528\u4e8e\u57fa\u56e0\u7ec4\u5b66\u7684\u53d1\u73b0\u4efb\u52a1\uff0c\u4f8b\u5982\u9884\u6d4b\u548c\u8bc6\u522b\u65b0\u7684\u9057\u4f20\u5143\u4ef6\u6216\u8868\u578b\u7279\u5f81\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4f8b\u5982\uff0cEvo 2\u5728\u5b66\u4e60\u57fa\u56e0\u7ec4\u6570\u636e\u65f6\uff0c\u80fd\u591f\u81ea\u52a8\u8bc6\u522b\u5e76\u6fc0\u6d3b\u4e0e\u566c\u83cc\u4f53\u76f8\u5173\u7684\u7279\u5f81\uff0c\u8fd9\u4e9b\u7279\u5f81\u4e0e\u566c\u83cc\u4f53\u533a\u57df\u4ee5\u53caCRISPR\u9635\u5217\u4e2d\u7684\u95f4\u9694\u5e8f\u5217\u6709\u5173\u3002\u7c7b\u4f3c\u5730\uff0cEvo 2\u8fd8\u80fd\u591f\u8bc6\u522b\u4e0e\u86cb\u767d\u8d28\u4e8c\u7ea7\u7ed3\u6784\uff08\u5982\u03b1\u87ba\u65cb\u548c\u03b2\u6298\u53e0\uff09\u76f8\u5173\u7684\u7279\u5f81\uff0c\u8fdb\u4e00\u6b65\u8bc1\u660e\u4e86\u57fa\u56e0\u7ec4\u8bed\u8a00\u6a21\u578b\u80fd\u591f\u8d85\u8d8aDNA\u5e8f\u5217\u672c\u8eab\uff0c\u7406\u89e3\u751f\u7269\u5b66\u7ed3\u6784\u4fe1\u606f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4e94\u3001\u8868\u89c2\u57fa\u56e0\u7ec4\u751f\u6210\u4e0e\u63a8\u7406\u5f15\u5bfc<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Evo 2\u4e0d\u4ec5\u53ef\u4ee5\u751f\u6210DNA\u5e8f\u5217\uff0c\u8fd8\u80fd\u591f\u901a\u8fc7\u63a8\u7406\u5f15\u5bfc\u6280\u672f\u751f\u6210\u8868\u89c2\u57fa\u56e0\u7ec4\u7ed3\u6784\u3002\u8868\u89c2\u57fa\u56e0\u7ec4\u7684\u8c03\u63a7\u6d89\u53caDNA\u7684\u5316\u5b66\u4fee\u9970\uff0c\u5982DNA\u7532\u57fa\u5316\u548c\u7ec4\u86cb\u767d\u4fee\u9970\uff0c\u8fd9\u4e9b\u4fee\u9970\u5bf9\u57fa\u56e0\u8868\u8fbe\u5177\u6709\u91cd\u8981\u5f71\u54cd\u3002\u5728\u8fd9\u9879\u7814\u7a76\u4e2d\uff0cEvo 2\u88ab\u7528\u6765\u751f\u6210\u5177\u6709\u7279\u5b9a\u67d3\u8272\u8d28\u53ef\u53ca\u6027\u6a21\u5f0f\u7684DNA\u5e8f\u5217\u3002\u67d3\u8272\u8d28\u53ef\u53ca\u6027\u662f\u6307DNA\u662f\u5426\u80fd\u88ab\u8f6c\u5f55\u673a\u68b0\u6240\u63a5\u89e6\u5230\uff0c\u4ece\u800c\u5f71\u54cd\u57fa\u56e0\u7684\u8868\u8fbe\u3002\u901a\u8fc7\u7ed3\u5408\u5916\u90e8\u7684\u8868\u89c2\u57fa\u56e0\u7ec4\u9884\u6d4b\u6a21\u578b\uff08\u5982Enformer\u548cBorzoi\uff09\uff0cEvo 2\u80fd\u591f\u5728\u751f\u6210DNA\u5e8f\u5217\u7684\u540c\u65f6\uff0c\u4f18\u5316\u8fd9\u4e9b\u5e8f\u5217\u7684\u67d3\u8272\u8d28\u53ef\u53ca\u6027\uff0c\u4f7f\u5176\u7b26\u5408\u9884\u8bbe\u7684\u6a21\u5f0f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7814\u7a76\u56e2\u961f\u4f7f\u7528\u4e86\u4e00\u4e2a\u201c\u675f\u641c\u7d22\u201d\u7b97\u6cd5\uff0c\u901a\u8fc7\u5bf9\u90e8\u5206\u751f\u6210\u7684DNA\u5e8f\u5217\u8fdb\u884c\u8bc4\u4f30\uff0c\u9009\u62e9\u6700\u7b26\u5408\u671f\u671b\u67d3\u8272\u8d28\u6a21\u5f0f\u7684\u5e8f\u5217\u3002\u8fd9\u4e2a\u65b9\u6cd5\u4e0d\u4ec5\u80fd\u751f\u6210\u7279\u5b9a\u533a\u57df\u7684\u67d3\u8272\u8d28\u5f00\u653e\u533a\u57df\uff0c\u8fd8\u53ef\u4ee5\u63a7\u5236\u67d3\u8272\u8d28\u95ed\u5408\u533a\u57df\u7684\u957f\u5ea6\u548c\u4f4d\u7f6e\uff0c\u6700\u7ec8\u751f\u6210\u5177\u6709\u7279\u5b9a\u529f\u80fd\u7684\u8868\u89c2\u57fa\u56e0\u7ec4\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u516d\u3001\u8ba8\u8bba<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Evo 2\u5c55\u793a\u4e86\u57fa\u56e0\u7ec4\u8bed\u8a00\u6a21\u578b\u5728\u751f\u7269\u5b66\u9886\u57df\u7684\u5e7f\u6cdb\u5e94\u7528\u6f5c\u529b\u3002\u5176\u901a\u8fc7\u5728\u8d85\u5927\u89c4\u6a21\u7684\u57fa\u56e0\u7ec4\u6570\u636e\u96c6\u4e0a\u8bad\u7ec3\uff0c\u80fd\u591f\u5728\u5206\u5b50\u3001\u7ec6\u80de\u4ee5\u53ca\u6709\u673a\u4f53\u5c42\u9762\u9884\u6d4b\u57fa\u56e0\u7a81\u53d8\u7684\u5f71\u54cd\uff0c\u5c24\u5176\u5728\u975e\u7f16\u7801\u533a\u57df\u7684\u9884\u6d4b\u65b9\u9762\uff0cEvo 2\u8d85\u8d8a\u4e86\u73b0\u6709\u7684\u5176\u4ed6\u57fa\u56e0\u7ec4\u8bed\u8a00\u6a21\u578b\u3002Evo 2\u4e0d\u4ec5\u5728\u201c\u96f6\u6837\u672c\uff08zeor-shot\uff09\u201d\u53d8\u5f02\u6548\u5e94\u9884\u6d4b\u4e2d\u53d6\u5f97\u4e86\u663e\u8457\u8fdb\u5c55\uff0c\u8fd8\u80fd\u591f\u751f\u6210\u5177\u6709\u751f\u7269\u5b66\u529f\u80fd\u548c\u81ea\u7136\u6027\u7684\u5168\u57fa\u56e0\u7ec4\u5e8f\u5217\u3002\u6b64\u5916\uff0cEvo 2\u5728\u63a8\u7406\u65f6\u8fdb\u884c\u7684\u8868\u89c2\u57fa\u56e0\u7ec4\u8bbe\u8ba1\uff0c\u5c55\u793a\u4e86\u5b83\u5728\u590d\u6742\u751f\u7269\u5b66\u7279\u6027\u8bbe\u8ba1\u4e2d\u7684\u5de8\u5927\u6f5c\u529b\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4e03\u3001\u7ed3\u8bba<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Evo 2\u662f\u4e00\u4e2a\u5f3a\u5927\u7684\u751f\u7269\u5b66\u57fa\u7840\u6a21\u578b\uff0c\u5b83\u5728\u9884\u6d4b\u57fa\u56e0\u53d8\u5f02\u6548\u5e94\u3001\u751f\u6210\u57fa\u56e0\u7ec4\u5e8f\u5217\u4ee5\u53ca\u8bbe\u8ba1\u8868\u89c2\u57fa\u56e0\u7ec4\u7b49\u4efb\u52a1\u4e2d\u8868\u73b0\u51fa\u4e86\u5353\u8d8a\u7684\u80fd\u529b\u3002Evo 2\u7684\u53d1\u5e03\u4e0d\u4ec5\u4e3a\u57fa\u56e0\u7ec4\u5b66\u7814\u7a76\u63d0\u4f9b\u4e86\u65b0\u7684\u5de5\u5177\uff0c\u4e5f\u4e3a\u5408\u6210\u751f\u7269\u5b66\u3001\u4e2a\u6027\u5316\u533b\u7597\u548c\u57fa\u56e0\u7ec4\u8bbe\u8ba1\u7b49\u9886\u57df\u63d0\u4f9b\u4e86\u91cd\u8981\u652f\u6301\u3002\u672a\u6765\uff0cEvo 2\u5c06\u7ed3\u5408\u66f4\u591a\u751f\u7269\u5b66\u6570\u636e\u548c\u8ba1\u7b97\u6280\u672f\uff0c\u63a8\u52a8\u57fa\u56e0\u7ec4\u5b66\u548c\u751f\u7269\u5b66\u8bbe\u8ba1\u7684\u667a\u80fd\u5316\u53d1\u5c55\uff0c\u5e2e\u52a9\u7814\u7a76\u4eba\u5458\u89e3\u9501\u751f\u547d\u7684\u590d\u6742\u6027\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\">\u76f8\u5173\u9605\u8bfb\uff1a<strong><a href=\"https:\/\/nullthought.net\/?p=5103\" target=\"_blank\" rel=\"noreferrer noopener\">Evo\uff1a\u57fa\u56e0\u7ec4\u5c3a\u5ea6\u4e0a\u7684\u751f\u6210\u5f0fAI\u751f\u7269\u57fa\u7840\u6a21\u578b<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u8bba\u6587Genome modeling and design across all domains of life [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[8,36],"tags":[39,95,45,90],"class_list":["post-5678","post","type-post","status-publish","format-standard","hentry","category-tech","category-36","tag-ai","tag-transformer","tag-medicine","tag-multimodal"],"rttpg_featured_image_url":null,"rttpg_author":{"display_name":"NullThought","author_link":"https:\/\/nullthought.net\/?author=1"},"rttpg_comment":0,"rttpg_category":"<a href=\"https:\/\/nullthought.net\/?cat=8\" rel=\"category\">Tech<\/a> <a href=\"https:\/\/nullthought.net\/?cat=36\" rel=\"category\">\u79d1\u5b66<\/a>","rttpg_excerpt":"\u8bba\u6587Genome modeling and design across all domains of life&hellip;","_links":{"self":[{"href":"https:\/\/nullthought.net\/index.php?rest_route=\/wp\/v2\/posts\/5678","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nullthought.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nullthought.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nullthought.net\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nullthought.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5678"}],"version-history":[{"count":1,"href":"https:\/\/nullthought.net\/index.php?rest_route=\/wp\/v2\/posts\/5678\/revisions"}],"predecessor-version":[{"id":5684,"href":"https:\/\/nullthought.net\/index.php?rest_route=\/wp\/v2\/posts\/5678\/revisions\/5684"}],"wp:attachment":[{"href":"https:\/\/nullthought.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5678"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nullthought.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=5678"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nullthought.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=5678"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}