{"id":2511,"date":"2022-05-20T16:02:44","date_gmt":"2022-05-20T08:02:44","guid":{"rendered":"https:\/\/nullthought.net\/?p=2511"},"modified":"2024-07-11T12:08:00","modified_gmt":"2024-07-11T04:08:00","slug":"mrna%e6%8a%80%e6%9c%af%e5%ae%9e%e7%8e%b0%e4%b8%80%e4%ba%ba%e4%b8%80%e8%8d%afone-vaccine-per-patient","status":"publish","type":"post","link":"https:\/\/nullthought.net\/?p=2511","title":{"rendered":"mRNA\u6280\u672f\u5b9e\u73b0\u4e00\u4eba\u4e00\u836f(One vaccine per patient)"},"content":{"rendered":"\n<p>Melissa J. Moore\u662fModerna\u7684\u9996\u5e2d\u79d1\u5b66\u5b98(Chief Scientific Officer)\uff0c\u5979\u8fd1\u671f\u5728TED\u8bb2\u575b\u4e0a\u53d1\u8868\u4e86\u4e3b\u9898\u4e3a\u201c<a rel=\"noreferrer noopener\" href=\"https:\/\/www.youtube.com\/watch?v=h5D3mv8ewCY&amp;t=309s\" target=\"_blank\">mRNA\u533b\u7597\u5982\u4f55\u6539\u53d8\u4e16\u754c<\/a>\u201d\u7684\u6f14\u8bb2\u3002\u542c\u4e86\u5176\u6f14\u8bb2\uff0c\u5bf9mRNA\u6709\u4e86\u4e00\u70b9\u513f\u79d1\u666e\u6027\u4e86\u89e3\u3002\u81ea\u5df1\u5bf9\u533b\u5b66\u4e00\u7a8d\u4e0d\u901a\uff0c\u4f46\u4e5f\u611f\u5230\u6f14\u8bb2\u5185\u5bb9\u6781\u5177\u51b2\u51fb\u529b\u3002\u7565\u603b\u7ed3\u51e0\u70b9\uff1a<\/p>\n\n\n\n<p>1.mRNA\u67d0\u79cd\u610f\u4e49\u4e0a\u53ef\u4ee5\u8bf4\u662f\u2019language of life(\u751f\u547d\u8bed\u8a00)\u2019\uff0c\u8fd9\u6837\u7684\u5b9a\u4e49\u51f8\u663e\u4e86mRNA\u6280\u672f\u7684\u5de8\u5927\u4ef7\u503c\uff1b<br>2.mRNA\u75ab\u82d7\u73b0\u5728\u53ef\u4ee5\u57281\u4e2a\u5c0f\u65f6\u5185\u8bbe\u8ba1\u51fa\u6765\uff0c45\u5929\u5185\u5b9e\u73b0\u4e34\u5e8a\u5e94\u7528\uff1b<br>3.\u5bf9\u4e8e\u764c\u75c7\uff0c\u672a\u6765\u53ef\u4ee5\u5b9e\u73b0\u5feb\u901f\u4e2a\u6027\u5316\u533b\u7597\uff0c\u505a\u5230\u4e00\u4eba\u4e00\u836f(one vaccine for one patient)\u3002mRNA\u53ef\u4ee5\u4e09\u79cd\u65b9\u5f0f\u5bf9\u80bf\u7624\u7ec6\u80de\u4ea7\u751f\u4f5c\u7528\uff1a1)\u8ba9\u80bf\u7624\u7ec6\u80de\u81ea\u6211\u7834\u73af\uff1b2)\u8bf1\u5bfc\u80bf\u7624\u7ec6\u80de\u53d1\u51fa\u4fe1\u53f7\uff0c\u8ba9\u4eba\u4f53\u514d\u75ab\u7cfb\u7edf\u5bf9\u5176\u53d1\u8d77\u653b\u51fb\uff1b3)\u538b\u5236\u4eba\u4f53\u7684\u8fc7\u5ea6\u81ea\u52a8\u514d\u75ab\u53cd\u5e94\u3002<br>4.\u91c7\u7528mRNA multiplex\u6280\u672f\u53ef\u4ee5\u8bbe\u8ba1\u751f\u4ea7\u51fa\u7ec4\u5408\u75ab\u82d7\uff1b<br>5.mRNA\u75ab\u82d7\u7684\u6574\u5957\u751f\u4ea7\u8bbe\u5907\u53ef\u96c6\u6210\u5230\u4e00\u4e2a\u96c6\u88c5\u7bb1\u5185\uff0c\u53ef\u5feb\u901f\u90e8\u7f72\u5230\u4efb\u4f55\u5730\u65b9\uff1b<br>6.<strong>mRNA\u544a\u8bc9\/\u6559\u5bfc(teach)\u6211\u4eec\u7684\u8eab\u4f53\u5982\u4f55\u81ea\u5df1\u53bb\u5bf9\u6297\u75be\u75c5<\/strong>\u3002\u6211\u4eec\u6b63\u5728\u8fdb\u5165\u4e00\u4e2a\u5168\u65b0\u7684\u533b\u7597\u65f6\u4ee3\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"576\" src=\"https:\/\/nullthought.net\/wp-content\/uploads\/2022\/05\/one-vaccine-per-patient-mRNA-medicine-1024x576.png\" alt=\"\" class=\"wp-image-2512\" srcset=\"https:\/\/nullthought.net\/wp-content\/uploads\/2022\/05\/one-vaccine-per-patient-mRNA-medicine-1024x576.png 1024w, https:\/\/nullthought.net\/wp-content\/uploads\/2022\/05\/one-vaccine-per-patient-mRNA-medicine-300x169.png 300w, https:\/\/nullthought.net\/wp-content\/uploads\/2022\/05\/one-vaccine-per-patient-mRNA-medicine-768x432.png 768w, https:\/\/nullthought.net\/wp-content\/uploads\/2022\/05\/one-vaccine-per-patient-mRNA-medicine-1536x864.png 1536w, https:\/\/nullthought.net\/wp-content\/uploads\/2022\/05\/one-vaccine-per-patient-mRNA-medicine.png 1920w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">One vaccine per patient<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"932\" height=\"401\" src=\"https:\/\/nullthought.net\/wp-content\/uploads\/2022\/05\/mRNA-multiplex.png\" alt=\"\" class=\"wp-image-2513\" srcset=\"https:\/\/nullthought.net\/wp-content\/uploads\/2022\/05\/mRNA-multiplex.png 932w, https:\/\/nullthought.net\/wp-content\/uploads\/2022\/05\/mRNA-multiplex-300x129.png 300w, https:\/\/nullthought.net\/wp-content\/uploads\/2022\/05\/mRNA-multiplex-768x330.png 768w\" sizes=\"auto, (max-width: 932px) 100vw, 932px\" \/><figcaption class=\"wp-element-caption\">mRNA multiplex<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"576\" src=\"https:\/\/nullthought.net\/wp-content\/uploads\/2022\/05\/how-mRNA-act-on-tumors-1024x576.png\" alt=\"\" class=\"wp-image-2514\" srcset=\"https:\/\/nullthought.net\/wp-content\/uploads\/2022\/05\/how-mRNA-act-on-tumors-1024x576.png 1024w, https:\/\/nullthought.net\/wp-content\/uploads\/2022\/05\/how-mRNA-act-on-tumors-300x169.png 300w, https:\/\/nullthought.net\/wp-content\/uploads\/2022\/05\/how-mRNA-act-on-tumors-768x432.png 768w, https:\/\/nullthought.net\/wp-content\/uploads\/2022\/05\/how-mRNA-act-on-tumors-1536x864.png 1536w, https:\/\/nullthought.net\/wp-content\/uploads\/2022\/05\/how-mRNA-act-on-tumors.png 1920w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">How mRNA act on tumors<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube aligncenter wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"How mRNA Medicine Will Change the World | Melissa J. Moore | TED\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/h5D3mv8ewCY?start=309&#038;feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><figcaption class=\"wp-element-caption\">How mRNA Medicine Will Change the World | Melissa J. Moore | TED<\/figcaption><\/figure>\n\n\n\n<p>\u8fd8\u6709\u4e00\u4e2a\u611f\u53d7\uff0c\u4e0d\u4e00\u5b9a\u5bf9\u3002mRNA\u6280\u672f\u662f\u751f\u7269\u5b66\u4e0e\u8ba1\u7b97\u673a\u79d1\u5b66\u7ed3\u5408\u7684\u5178\u578b\u4ee3\u8868\u3002<a href=\"https:\/\/zh.wikipedia.org\/zh-cn\/%E7%94%9F%E7%89%A9%E4%BF%A1%E6%81%AF%E5%AD%A6\" target=\"_blank\" rel=\"noreferrer noopener\">\u751f\u7269\u4fe1\u606f\u5b66(bioinformatics)<\/a>\u7684\u524d\u9014\u4e0d\u53ef\u9650\u91cf\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p>P.S., <a href=\"https:\/\/www.shanghai.gov.cn\/nw4411\/20240626\/f8f456e569e04885be5477c37879cd84.html\" target=\"_blank\" rel=\"noreferrer noopener\">\u80f0\u817a\u764cmRNA\u75ab\u82d7\u65b0\u7a81\u7834 \u745e\u91d1\u56e2\u961f\u5728\u56fd\u9645\u533b\u5b66\u9876\u520a\u53d1\u8868\u8bba\u6587<\/a>\uff1a<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>&#8230;&#8230;<\/p>\n\n\n\n<p>\u627e\u5230\u9776\u70b9\uff0c\u7ee7\u800c\u6cbb\u7597\u3002\u65b0\u53d1\u5e03\u7684mRNA\u80bf\u7624\u75ab\u82d7\u5c06\u7528\u4e8e\u80f0\u817a\u764c\u60a3\u8005\u7684\u6cbb\u7597\u9636\u6bb5\uff0c\u56e2\u961f\u671f\u5f85\u5728\u76f8\u5173\u4ea7\u54c1\u6279\u51c6\u4e0a\u5e02\u7684\u57fa\u7840\u4e0a\uff0c\u672a\u6765\u5b9e\u73b0\u76f8\u5173\u7597\u6cd5\u7684\u5e7f\u6cdb\u5e94\u7528\uff0c\u771f\u6b63\u4e3a\u80f0\u817a\u764c\u60a3\u8005\u5f62\u6210\u7cbe\u51c6\u5316\u201c\u4e00\u4eba\u4e00\u5242\u201d\u3002<\/p>\n<\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>Melissa J. Moore\u662fModerna\u7684\u9996\u5e2d\u79d1\u5b66\u5b98(Chief Scientific Officer [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[8],"tags":[45],"class_list":["post-2511","post","type-post","status-publish","format-standard","hentry","category-tech","tag-medicine"],"rttpg_featured_image_url":null,"rttpg_author":{"display_name":"NullThought","author_link":"https:\/\/nullthought.net\/?author=1"},"rttpg_comment":0,"rttpg_category":"<a href=\"https:\/\/nullthought.net\/?cat=8\" rel=\"category\">Tech<\/a>","rttpg_excerpt":"Melissa J. Moore\u662fModerna\u7684\u9996\u5e2d\u79d1\u5b66\u5b98(Chief Scientific Officer&hellip;","_links":{"self":[{"href":"https:\/\/nullthought.net\/index.php?rest_route=\/wp\/v2\/posts\/2511","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nullthought.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nullthought.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nullthought.net\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nullthought.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2511"}],"version-history":[{"count":4,"href":"https:\/\/nullthought.net\/index.php?rest_route=\/wp\/v2\/posts\/2511\/revisions"}],"predecessor-version":[{"id":3970,"href":"https:\/\/nullthought.net\/index.php?rest_route=\/wp\/v2\/posts\/2511\/revisions\/3970"}],"wp:attachment":[{"href":"https:\/\/nullthought.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2511"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nullthought.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2511"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nullthought.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2511"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}